Because human immunodeficiency virus 1 (HIV-1) has an RNA genome, it is no surprise that protein-RNA interactions play key roles both in the replication cycle of HIV-1 and in the host defense against HIV-1 infection. Research in our laboratory focuses on understanding the molecular details of how HIV-1 replication is regulated by these host and viral RNA-binding proteins, the identification of the RNA targets of these proteins, and the discovery of novel RNA-binding proteins that enhance or block HIV-1 replication.

 Sebla Kutluay, Ph.D. 
 Assistant Professor                        
 Campus Box 8230
660 S. Euclid Ave.
St. Louis, MO 63110.